CCP has gone on a rampage against Macro'ers and ISK sellers recently, banning up to 6000 accounts on a single day. The result? This image from the dev blog should help explain it:
CPU Per User dropped a huge amount in the days after the purge. That helps against lag, desyncs, etc.
Whoever says macro'ers don't hurt the game is wrong, wrong, wrong.
Read the whole thing. Lots of graphs.