So I bought a bunch of mods and implants in Jita the other day and was faced with the terror of trying to get them safely home without getting suicide ganked in transit. I didn't want to end up like the foolish guy transporting an alleged 14 billion in blueprints in a Iteron that gets blown up. There was three options available to me:
Prowler Blockade Runner - Fast, cloak, but thin defences. All it would take is one smartbombing battleship and my day would be ruined.
Mastadon Deep Space Transport - Much better defences, more likely to get scanned and setup for interception.
Fenrir Freighter - Best defences, hardest to suicide gank, but slowest and most likely to get scanned.
In the end I opted for light and cloaked and warped through high sec cloaked every second possible. I made it home without incident.